GPC Online offers 25 distinct science courses.
| ASTR 1010 | Astronomy of the Solar System |
| ASTR 1010L | Astronomy of the Solar System Laboratory |
| ASTR 1020 | Stellar & Galactic Astronomy |
| ASTR 1020L | Stellar & Galactic Astronomy Laboratory |
| BIOL 1402 | Cell Biology and Genetics |
| BIOL 1402L | Cell Biology and Genetics Laboratory |
| BIOL 1403 | Diversity in the Living World |
| BIOL 1403L | Diversity in the Living World Laboratory |
| BIOL 1611 | Human Anatomy and Physiology I |
| BIOL 1612 | Human Anatomy and Physiology II |
| BIOL 1913 | Microbiology |
| CHEM 1151 | Survey of Chemistry I |
| CHEM 1152 | Survey of Chemistry II |
| CHEM 1211 | Principles of Chemistry I |
| CHEM 1212 | Principles of Chemistry II |
| ENVS 1401 | Environmental Science |
| GEOL 1121 | Physical Geology |
| GEOL 1121L | Physical Geology Laboratory |
| GEOL 1122 | Historical Geology |
| GEOL 1122L | Historical Geology Laboratory |
| PHYS 1111 | Introductory Physics I |
| PHYS 1112 | Introductory Physics II |
| PHYS 2211 | Principles of Physics I |
| PHYS 2212 | Principles of Physics II |
Science Online: GPC Online offers the following lecture-lab pairs.
| ASTR 1010 | ASTR 1010L |
| ASTR 1020 | ASTR 1020L |
| BIOL 1402 | BIOL 1402L |
| BIOL 1403 | BIOL 1403L |
| GEOL 1121 | GEOL 1121L |
| GEOL 1122 | GEOL 1122L |
Science Online: GPC Online offers the following science lectures without an online laboratory. The labs for these classes are mandatory and are offered on-site at four of our GPC campuses.
| BIOL 1611 |
| BIOL 1612 |
| BIOL 1913 |
| CHEM 1151 |
| CHEM 1152 |
| CHEM 1211 |
| CHEM 1212 |
| ENVS 1401 |
| PHYS 1111 |
| PHYS 1112 |
| PHYS 2211 |
| PHYS 2212 |